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Research and Advances in Psychiatry

Psychopathological aspects in patients with complex partial epilepsy: a pilot study

Original Article, 62 - 67
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Although the psychopathological characterization of epilepsy has been largely discussed during the next decades, there is still a controversial debate, particularly regarding to its comorbidity with mood disorders. The aim of the study is to investigate psychopathological features in subjects with a history of seizure.
Material and methods: a sample of 62 outpatients with a diagnosis of complex partial epilepsy, progressively afferent to the Clinic of Neurophysiopathology at the Department of Neurology (General Hospital “G. Mazzini”, Teramo), were evaluatedaccording to the inclusion criteria. A total of 12 outpatients were finally recruited and assessed for impulsiveness (Barratt Impulsiveness Scale-11 [BIS-11]), alexithymia (Toronto Alexithymia Scale-20 [TAS-20]), temperamental traits (Modified Fatigue Impact Scale [MFIS] Temps-In), depressive symptoms (Hamilton Rating Scale for Depression [HRSD]), sleepiness (Epworth Sleepiness Scale [ESS]) and resilience (Connor-Davidson scale [CDS]).
Results: a moderate correlation between fatigue and depression was found and was not associated with a significant impairment of quality of life.
A moderate negative effect on cognitive functioning has been reported as well. A statistically correlation between depression and resilience represented another significant result (p<0.05).
Discussion: evidence so far available and preliminary findings coming from our pilot study demonstrate that epileptic patients may show a cluster of temperamental as well psychopathological conditions in comorbidity, especially depressive
symptomatology. Further studies should better investigate and detect the role of psychiatric conditions in epilepsy, particularly amongst subjects affected with temporal epilepsy.

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