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Research and Advances in Psychiatry

Treatment with vortioxetine in outpatients with anxiety and depressive disorders: a retrospective analysis

Original Articles, 18 - 21
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Vortioxetine is a novel antidepressant agent with multimodal action, combining serotonin transporter reuptake blockage and receptors modulation. This mechanism suggests a different antidepressant profile as compared with commonly used SSRIs / SNRIs. We investigated main clinical and demographic characteristics of subjects treated with vortioxetine.
We retrospectively reviewed data of individuals attending San Gerardo Hospital outpatient clinic (“Ambulatorio Vademecum”) for anxiety and depressive disorders. We estimated a reduction in prescription of additional psychopharmacological treatments, in particular anxiolytics, in subjects treated with vortioxetine. In addition, vortioxetine was preferably used for the treatment of depression, as compared with anxiety and adjustment disorders.
Since our data are preliminary and limited by important methodological issues, further studies based on a larger sample size, are needed to confirm the estimated trends.

Vol. 5 (No. 2) 2018 May - August

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